Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with Target = '1-deoxy-D-xylulose 5-phosphate reductoisomerase' and Ligand = 'BDBM50028309'
LigandPNGBDBM50028309(Fosmidomycin Sodium)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibitory activity against recombinant Trypanosoma cruzi (Trypanosoma cruzi) Trypanothione reductaseMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50028309(Fosmidomycin Sodium)copy SMILEScopy InChI
Affinity DataIC50: 49nMAssay Description:Antagonism of norepinephrine induced contraction of rat isolated thoracic aorta.More data for this Ligand-Target Pair
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Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)TBA
LigandPNGBDBM50028309(Fosmidomycin Sodium)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibitory activity against recombinant Trypanosoma cruzi (Trypanosoma cruzi) Trypanothione reductaseMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50028309(Fosmidomycin Sodium)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibition of Escherichia coli M15 recombinant IspC using 1-deoxy-D-xylulose 5-phosphate as substrate by photometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KP83RXPubMed
LigandPNGBDBM50028309(Fosmidomycin Sodium)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibition of recombinant Escherichia coli IspC expressed in Escherichia coli M15 using 1-deoxy-D-xylulose 5-phosphate as substrate by photometric as...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7N4ZPubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)TBA
LigandPNGBDBM50028309(Fosmidomycin Sodium)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis IspC expressed in Escherichia coli M15 using 1-deoxy-D-xylulose 5-phosphate as substrate by phot...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7N4ZPubMed