Found 1 Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM108088'
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH
US Patent
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH
US Patent
Affinity DataIC50: 31nMpH: 6.0 T: 2°CAssay Description:The inhibition of a microsomal preparation of 11β-HSD1 in the presence of 50% human plasma by compounds of the invention was measured.More data for this Ligand-Target Pair