Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM13754'
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM13754((5S)-2-{[(1S)-1-(2-fluorophenyl)ethyl]amino}-5-met...)copy SMILEScopy InChI
Affinity DataKi:  22nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in Escherichia coli using [3H]cortisone by scintillation proximity assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM13754((5S)-2-{[(1S)-1-(2-fluorophenyl)ethyl]amino}-5-met...)copy SMILEScopy InChI
Affinity DataKi:  22nM ΔG°:  -43.3kJ/molepH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair