Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM50067044'
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Wenzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50067044((1E,4E)-1,5-Bis-(4-hydroxy-phenyl)-penta-1,4-dien-...)copy SMILEScopy InChI
Affinity DataIC50: 832nMAssay Description:Inhibition of human 11beta-HSD1 transfected in CHOP cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27D2WJMPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Wenzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50067044((1E,4E)-1,5-Bis-(4-hydroxy-phenyl)-penta-1,4-dien-...)copy SMILEScopy InChI
Affinity DataIC50: 986nMAssay Description:Inhibition of 11beta-HSD1 in Sprague-Dawley rat leydig cells at 100 uMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27D2WJMPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Wenzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50067044((1E,4E)-1,5-Bis-(4-hydroxy-phenyl)-penta-1,4-dien-...)copy SMILEScopy InChI
Affinity DataIC50: 4.42E+3nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using [3H]-cortisone as substrate assessed as formation of cortisol after 60 to 90 mins by radiom...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27D2WJMPubMed