Found 4 Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM50188389' Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University of Innsbruck
Curated by ChEMBL
University of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 2.03E+3nMAssay Description:Inhibition of human recombinant 11betaHSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
University of Innsbruck
Curated by ChEMBL
University of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of 11-beta-HSD1-dependent cortisone conversion to cortisol in mouse intact 3T3 L1 cellsMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
University of Innsbruck
Curated by ChEMBL
University of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 4.17E+3nMAssay Description:Inhibition of 11-beta-HSD1-dependent cortisone conversion to cortisol in mouse intact C2C12 cellsMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University of Innsbruck
Curated by ChEMBL
University of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 5.21E+3nMAssay Description:Inhibition of human recombinant 11-beta-HSD1 transfected in intact HEK293 cellsMore data for this Ligand-Target Pair
