Compile Data Set for Download or QSAR
Found 5 Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM50202102'
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202102(CHEMBL375156 | N-(5-Hydroxy-adamantan-2-yl)-2-[4-(...)copy SMILEScopy InChI
Affinity DataKi:  4nMAssay Description:Inhibitory activity against rat 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60NQNPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202102(CHEMBL375156 | N-(5-Hydroxy-adamantan-2-yl)-2-[4-(...)copy SMILEScopy InChI
Affinity DataKi:  5nMAssay Description:Inhibition of human 11beta-HSD1 expressed in E. coli by SPAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60NQNPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202102(CHEMBL375156 | N-(5-Hydroxy-adamantan-2-yl)-2-[4-(...)copy SMILEScopy InChI
Affinity DataKi:  15nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in E. coli by SPAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60NQNPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202102(CHEMBL375156 | N-(5-Hydroxy-adamantan-2-yl)-2-[4-(...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells assessed as conversion of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2GN7PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202102(CHEMBL375156 | N-(5-Hydroxy-adamantan-2-yl)-2-[4-(...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells by FPIAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60NQNPubMed