Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM50392235'
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM50392235(CHEMBL2153192 | US8673938, 4)copy SMILEScopy InChI
Affinity DataIC50: 198nMAssay Description:The conversion of cortisone to the active steroid cortisol by 11βHSD1 oxo-reductase activity, can be measured using a competitive homogeneous ti...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2610Z0DUS Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM50392235(CHEMBL2153192 | US8673938, 4)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of N-terminal His6-tagged full length human 11betaHSD1 expressed in baculovirus infected cells using cortisone as substrate after 25 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1RTKPubMed