Found 2 Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM50430135'
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Toray Industries, Inc.
Curated by ChEMBL
Toray Industries, Inc.
Curated by ChEMBL
Affinity DataIC50: 3.80nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone and NADPH as substrate by HTRF assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Toray Industries, Inc.
Curated by ChEMBL
Toray Industries, Inc.
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in HEK293 cells using cortisone and NADPH as substrate by HTRF assayMore data for this Ligand-Target Pair