Found 3 Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM50504041' Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataKi: 620nMAssay Description:Inhibition of N-terminal MKHQHQHQHQHQHQQPL-tagged 11beta-HSD1 C272S mutant (unknown origin) expressed in Escherichia coli BL21 (DE3) using cortisol a...More data for this Ligand-Target Pair
3D Structure (crystal)Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of 11beta-HSD1 in human microsomes using [3H] cortisone as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of N-terminal MKHQHQHQHQHQHQQPL-tagged 11beta-HSD1 C272S mutant (unknown origin) expressed in Escherichia coli BL21 (DE3) using cortisol a...More data for this Ligand-Target Pair
