Compile Data Set for Download or QSAR
Found 1 Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1 [24-292,C272S]' and Ligand = 'BDBM32550'
Target11-beta-hydroxysteroid dehydrogenase 1 [24-292,C272S](Homo sapiens (Human))
Amgen Inc.

LigandPNGBDBM32550(arylsulfonylpiperazine, 22)copy SMILEScopy InChI
Affinity DataIC50: 7nM EC50:  241nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J964Q1PubMed