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Compile Data Set for Download or QSAR
Found
1
Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1 [24-292,C272S]' and Ligand = 'BDBM32573'
Target
11-beta-hydroxysteroid dehydrogenase 1 [24-292,C272S]
(Homo sapiens (Human))
Amgen Inc.
Ligand
BDBM32573
(CHEMBL427896 | arylsulfonylpiperazine, 45)
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Affinity Data
IC50: 3nM EC50: 57nM
Assay Description:
Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...
More data for this Ligand-Target Pair
Target Info
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Ligand Info
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In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2J964Q1
PubMed
MMDB
PDB
3D Structure (crystal)