Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase type 2' and Ligand = 'BDBM50185127'
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50185127((3beta,20beta)-20-carboxy-11-oxo-30-norolean-12-en...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human microsomal 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1T1DPubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50185127((3beta,20beta)-20-carboxy-11-oxo-30-norolean-12-en...)copy SMILEScopy InChI
Affinity DataEC50:  1nMAssay Description:Inhibition of human 11beta-HSD2 expressed in HEK293 cells assessed as [3H]cortisol production after 60 mins by SPAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7PGXPubMed