BindingDB PrimarySearch

Found 1 Enz. Inhib. hit(s) with Target = '3-hydroxy-3-methylglutaryl-coenzyme A reductase' and Ligand = 'BDBM18384'

3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Pfizer

BDBM18384(Alkyl substituted pyrrole compound, 29c | sodium (...)copy SMILEScopy InChI

IC50: 1.60nMpH: 7.2 T: 2°CAssay Description:Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme source...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

KEGG PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q23J3B7GPubMed