Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = '3-hydroxy-3-methylglutaryl-coenzyme A reductase' and Ligand = 'BDBM50014669'
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50014669(6-[2-(4'-Fluoro-3,5,3'-trimethyl-biphenyl-2-yl)-vi...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RV0MQXPubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50014669(6-[2-(4'-Fluoro-3,5,3'-trimethyl-biphenyl-2-yl)-vi...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RV0MQXPubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50014669(6-[2-(4'-Fluoro-3,5,3'-trimethyl-biphenyl-2-yl)-vi...)copy SMILEScopy InChI
Affinity DataIC50: 7.60nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RV0MQXPubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50014669(6-[2-(4'-Fluoro-3,5,3'-trimethyl-biphenyl-2-yl)-vi...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Ability to inhibit HMG-CoA reductase (HMGR) by cholesterol synthesis inhibition screen (CSI) in ratsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XG9RR6PubMed