Compile Data Set for Download or QSAR
Found 5 Enz. Inhib. hit(s) with Target = '3-hydroxy-3-methylglutaryl-coenzyme A reductase' and Ligand = 'BDBM50368147'
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Hoechst AG

Curated by ChEMBL
LigandPNGBDBM50368147((+)-(3R,5S)-fluvastatin | (3R,5S)-fluvastatin | (3...)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:In vitro inhibition of solubilized HMG-CoA reductase in rat liver.More data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Hoechst AG

Curated by ChEMBL
LigandPNGBDBM50368147((+)-(3R,5S)-fluvastatin | (3R,5S)-fluvastatin | (3...)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibitory activity against partially purified rat liver HMG-CoA reductase in vitro; 0.0015-0.0040More data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Hoechst AG

Curated by ChEMBL
LigandPNGBDBM50368147((+)-(3R,5S)-fluvastatin | (3R,5S)-fluvastatin | (3...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of rat HMG-CoA reductase using 0.37 MBq DL-[3-14C]HMG-CoAMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50368147((+)-(3R,5S)-fluvastatin | (3R,5S)-fluvastatin | (3...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibitory concentration against 3-hydroxy-3-methylglutaryl-CoA reductaseMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Hoechst AG

Curated by ChEMBL
LigandPNGBDBM50368147((+)-(3R,5S)-fluvastatin | (3R,5S)-fluvastatin | (3...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Ability to inhibit microsomal preparation of HMG-CoA reductase in rat liver.More data for this Ligand-Target Pair