Found 3 Enz. Inhib. hit(s) with Target = '3-hydroxy-3-methylglutaryl-coenzyme A reductase' and Ligand = 'BDBM50432558' Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
ACADEMIA SINICA; NATIONAL TAIWAN UNIVERSITY
US Patent
ACADEMIA SINICA; NATIONAL TAIWAN UNIVERSITY
US Patent
Affinity DataIC50: 43.7nMpH: 7.4Assay Description:The HMGR activity was performed using HMG-CoA reductase assay kit from Sigma-Aldrich with the human recombinant protein or 100 μg total cell lys...More data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
ACADEMIA SINICA; NATIONAL TAIWAN UNIVERSITY
US Patent
ACADEMIA SINICA; NATIONAL TAIWAN UNIVERSITY
US Patent
Affinity DataIC50: 44nMAssay Description:Inhibition of recombinant HMG-CoA reductase (unknown origin) after 10 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
ACADEMIA SINICA; NATIONAL TAIWAN UNIVERSITY
US Patent
ACADEMIA SINICA; NATIONAL TAIWAN UNIVERSITY
US Patent
Affinity DataIC50: 1.49E+4nMAssay Description:Inhibition of HMG-CoA reductase in human A549 cells after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
