Compile Data Set for Download or QSAR
Found 9 Enz. Inhib. hit(s) with Target = '3-oxo-5-alpha-steroid 4-dehydrogenase 1' and Ligand = 'BDBM50043604'
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50043604((8S,9S,10R,13S,14S,17S)-17-(tert-butylcarbamoyl)-1...)copy SMILEScopy InChI
Affinity DataKi:  410nMAssay Description:Inhibition of type-1 human steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ661K
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50043604((8S,9S,10R,13S,14S,17S)-17-(tert-butylcarbamoyl)-1...)copy SMILEScopy InChI
Affinity DataKi:  410nMAssay Description:Apparent inhibition constant towards human Steroid 5-alpha-reductase type IMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4X8P
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50043604((8S,9S,10R,13S,14S,17S)-17-(tert-butylcarbamoyl)-1...)copy SMILEScopy InChI
Affinity DataKi:  1.60E+3nMAssay Description:In vitro inhibitory activity against human type 1 5-alpha reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q228088WPubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50043604((8S,9S,10R,13S,14S,17S)-17-(tert-butylcarbamoyl)-1...)copy SMILEScopy InChI
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of recombinant human 5-alpha reductase-1 at a concentration of 5 microL after preincubation for 10 minutesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0F76PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Rattus norvegicus)
Universität des Saarlandes

Curated by ChEMBL
LigandPNGBDBM50043604((8S,9S,10R,13S,14S,17S)-17-(tert-butylcarbamoyl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Inhibitory activity against rat Steroid 5-alpha-reductase type I using 18213 3H testosterone 210 nM as substrateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P84B24PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50043604((8S,9S,10R,13S,14S,17S)-17-(tert-butylcarbamoyl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of type 1 steroid-5-alpha-reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K35V8RPubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50043604((8S,9S,10R,13S,14S,17S)-17-(tert-butylcarbamoyl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human Steroid 5-alpha-reductase type IMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G161G8PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50043604((8S,9S,10R,13S,14S,17S)-17-(tert-butylcarbamoyl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory concentration of the compound against human Steroid 5-alpha-reductase type I in DU 145 cell culture using 3H androstenedione 5 nM as subs...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P84B24PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50043604((8S,9S,10R,13S,14S,17S)-17-(tert-butylcarbamoyl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of recombinant Steroid 5-alpha-reductase type I was evaluated as binding affinity of the compoundMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C829XCPubMed