Compile Data Set for Download or QSAR
Found 9 Enz. Inhib. hit(s) with Target = '3-oxo-5-alpha-steroid 4-dehydrogenase 2' and Ligand = 'BDBM50043604'
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50043604((8S,9S,10R,13S,14S,17S)-17-(tert-butylcarbamoyl)-1...)copy SMILEScopy InChI
Affinity DataKi:  0.200nMAssay Description:Apparent inhibition constant towards human Steroid 5-alpha-reductase type 2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4X8P
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50043604((8S,9S,10R,13S,14S,17S)-17-(tert-butylcarbamoyl)-1...)copy SMILEScopy InChI
Affinity DataKi:  0.200nMAssay Description:Inhibition of type-2 human steroid 5-alpha-reductase.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ661K
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50043604((8S,9S,10R,13S,14S,17S)-17-(tert-butylcarbamoyl)-1...)copy SMILEScopy InChI
Affinity DataKi:  30nMAssay Description:In vitro inhibitory activity against Steroid 5-alpha-reductase was determined in human prostatic tissue expressed as apparent inhibition constant; Ra...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25D8QSBPubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50043604((8S,9S,10R,13S,14S,17S)-17-(tert-butylcarbamoyl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 0.180nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q228088WPubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50043604((8S,9S,10R,13S,14S,17S)-17-(tert-butylcarbamoyl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 0.180nMAssay Description:Inhibitory activity measured on human steroid 5-alpha-reductase type 2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C829XCPubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50043604((8S,9S,10R,13S,14S,17S)-17-(tert-butylcarbamoyl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant human Steroid 5-alpha-reductase type 2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G161G8PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50043604((8S,9S,10R,13S,14S,17S)-17-(tert-butylcarbamoyl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of type 2 steroid-5-alpha-reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K35V8RPubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50043604((8S,9S,10R,13S,14S,17S)-17-(tert-butylcarbamoyl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against human Steroid 5-alpha-reductase type 2 using 18213 3H testosterone 210 nM as substrateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P84B24PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50043604((8S,9S,10R,13S,14S,17S)-17-(tert-butylcarbamoyl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant human 5-alpha reductase-2 at a concentration of 5 microL after preincubation for 10 minutesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0F76PubMed