Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 1A' and Ligand = 'BDBM423299'
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
NHWA PHARMA. CORPORATION

US Patent
LigandPNGBDBM423299(US10501452, Compound 5)copy SMILEScopy InChI
Affinity DataKi:  2.40nMAssay Description:5-HT1A: (1) The prepared membrane was applied with appropriate amount of buffer, and homogenizer was used for evenly dispersing. 15 tubes were mixed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BK1FR6US Patent
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
NHWA PHARMA. CORPORATION

US Patent
LigandPNGBDBM423299(US10501452, Compound 5)copy SMILEScopy InChI
Affinity DataKi:  9.10nMAssay Description:Displacement of [3H](+)8-OH-DPAT from rat cerebral cortex 5HT1A receptor measured after 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8K6MPubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))TBA
LigandPNGBDBM423299(US10501452, Compound 5)copy SMILEScopy InChI
Affinity DataIC50: 57nMAssay Description:Antagonist activity at human 5HT1A receptor expressed in CHO-K1 cells assessed as inhibition of 5HT-induced calcium flux incubated for 60 mins at 37 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8K6MPubMed