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Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
NEUROLIXIS; UNIVERSITE JAGELLONE
US Patent
NEUROLIXIS; UNIVERSITE JAGELLONE
US Patent
Affinity DataKi: 12nMAssay Description:5-HT1A: Radioligand binding was performed using membranes from CHO-K1 cells stably transfected with the human 5-HT1A receptor. All assays were carrie...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
NEUROLIXIS; UNIVERSITE JAGELLONE
US Patent
NEUROLIXIS; UNIVERSITE JAGELLONE
US Patent
Affinity DataKi: 14nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5HT1A receptor stably expressed in CHO-K1 cell membranes measured after 60 mins by microbeta2 sc...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
NEUROLIXIS; UNIVERSITE JAGELLONE
US Patent
NEUROLIXIS; UNIVERSITE JAGELLONE
US Patent
Affinity DataEC50: 933nMAssay Description:Biased agonist activity at human recombinant 5-HT1A receptor stably expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumu...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
NEUROLIXIS; UNIVERSITE JAGELLONE
US Patent
NEUROLIXIS; UNIVERSITE JAGELLONE
US Patent
Affinity DataEC50: 2.75E+3nMAssay Description:Biased agonist activity at Gal4-VP16 transcription factor linked human 5-HT1A receptor expressed in human U2OS cells assessed as stimulation of beta-...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
NEUROLIXIS; UNIVERSITE JAGELLONE
US Patent
NEUROLIXIS; UNIVERSITE JAGELLONE
US Patent
Affinity DataEC50: 52nMAssay Description:Biased agonist activity at human recombinant 5-HT1A receptor stably expressed in CHO-K1 cells assessed as increase in ERK1/2 phosphorylation levels i...More data for this Ligand-Target Pair
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