Compile Data Set for Download or QSAR
Found 11 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 1A' and Ligand = 'BDBM50011247'
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universit£ di Napoli Federico II

Curated by ChEMBL
LigandPNGBDBM50011247(7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol...)copy SMILEScopy InChI
Affinity DataKi:  0.800nMAssay Description:Binding affinity to 5HT1A receptor in Sprague-Dawley rat brain cortex homogenates after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M32W4JPubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universit£ di Napoli Federico II

Curated by ChEMBL
LigandPNGBDBM50011247(7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol...)copy SMILEScopy InChI
Affinity DataKi:  1.20nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A receptor of rat hippocampus tissue.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50NPWPubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universit£ di Napoli Federico II

Curated by ChEMBL
LigandPNGBDBM50011247(7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol...)copy SMILEScopy InChI
Affinity DataKi:  1.80nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959GJHPubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universit£ di Napoli Federico II

Curated by ChEMBL
LigandPNGBDBM50011247(7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol...)copy SMILEScopy InChI
Affinity DataKi:  1.80nMAssay Description:Compound was evaluated for inhibiting the binding of [3H]- 8-OH-DPAT to 5-HT1A-receptor from cerebral cortex membranes of ratMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416X0N
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universit£ di Napoli Federico II

Curated by ChEMBL
LigandPNGBDBM50011247(7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol...)copy SMILEScopy InChI
Affinity DataKi:  1.80nMAssay Description:Binding affinity against rat hippocampal 5-hydroxytryptamine 1A (5-HT1A) receptor determined using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8G6CPubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universit£ di Napoli Federico II

Curated by ChEMBL
LigandPNGBDBM50011247(7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol...)copy SMILEScopy InChI
Affinity DataKi:  4.10nMAssay Description:Binding affinity at 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in rat brain.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0GRBPubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universit£ di Napoli Federico II

Curated by ChEMBL
LigandPNGBDBM50011247(7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol...)copy SMILEScopy InChI
Affinity DataKi:  6.10nMAssay Description:Binding affinity at 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in rat brain.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0GRBPubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50011247(7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol...)copy SMILEScopy InChI
Affinity DataKi:  7.60nMAssay Description:Displacement of [3H]-5-carboxamidotryptamine from human 5-HT1A receptor expressed in HEK293T cell membranes incubated for 90 mins by scintillation co...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SX6HRDPubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universit£ di Napoli Federico II

Curated by ChEMBL
LigandPNGBDBM50011247(7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol...)copy SMILEScopy InChI
Affinity DataKi:  8.40nMAssay Description:In vitro binding affinity against 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPATMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MP52CRPubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universit£ di Napoli Federico II

Curated by ChEMBL
LigandPNGBDBM50011247(7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:In vitro Inhibitory activity tested at 5-hydroxytryptamine 1A receptor binding site in ratMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23J3DJBPubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universit£ di Napoli Federico II

Curated by ChEMBL
LigandPNGBDBM50011247(7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol...)copy SMILEScopy InChI
Affinity DataIC50: 6.5nMAssay Description:Concentration of compound required to inhibit cortical 5-hydroxytryptamine 1A receptor binding sites in rat brain was evaluatedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2736PW1PubMed