Compile Data Set for Download or QSAR
Found 18 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 1A' and Ligand = 'BDBM50019443'
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
INSERM U.288

Curated by PDSP Ki Database
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)copy SMILEScopy InChI
Affinity DataKi:  15nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N29VFSPubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
INSERM U.288

Curated by PDSP Ki Database
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)copy SMILEScopy InChI
Affinity DataKi:  17.8nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M043X2PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)copy SMILEScopy InChI
Affinity DataKi:  20nMAssay Description:Evaluated for the binding affinity to hippocampus striatal membranes at 5-hydroxytryptamine 1A receptor binding site by using [3H]-8-OH- DPAT as a ra...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K4BS7PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)copy SMILEScopy InChI
Affinity DataKi:  22nMAssay Description:Binding affinity of a compound to rat brain 5-hydroxytryptamine 1A (serotonin) receptor assayed by radiolabeled [3H]-8-OH-DPAT ligand displacementMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0K7VPubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
INSERM U.288

Curated by PDSP Ki Database
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)copy SMILEScopy InChI
Affinity DataKi:  22nMAssay Description:Displacement of [3H]DPAT from human 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2GG0PubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
INSERM U.288

Curated by PDSP Ki Database
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)copy SMILEScopy InChI
Affinity DataKi:  24nMAssay Description:Displacement of specific [3H]- 5-HT binding to cloned human 5-hydroxytryptamine 1A receptor stably expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W37WVBPubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
INSERM U.288

Curated by PDSP Ki Database
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)copy SMILEScopy InChI
Affinity DataKi:  28nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ64JGPubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
INSERM U.288

Curated by PDSP Ki Database
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)copy SMILEScopy InChI
Affinity DataKi:  28.2nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M043X2PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)copy SMILEScopy InChI
Affinity DataKi:  31nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q269723DPubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
INSERM U.288

Curated by PDSP Ki Database
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)copy SMILEScopy InChI
Affinity DataKi:  33.1nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M043X2PubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
INSERM U.288

Curated by PDSP Ki Database
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)copy SMILEScopy InChI
Affinity DataKi:  33.3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3JPGPubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
INSERM U.288

Curated by PDSP Ki Database
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)copy SMILEScopy InChI
Affinity DataKi:  37.1nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M043X2PubMed
Target5-hydroxytryptamine receptor 1A(pigeon)
CNS-Pharmacology

Curated by PDSP Ki Database
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)copy SMILEScopy InChI
Affinity DataKi:  47nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2319TDMPubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
INSERM U.288

Curated by PDSP Ki Database
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)copy SMILEScopy InChI
Affinity DataKi:  61.1nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3JPGPubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
INSERM U.288

Curated by PDSP Ki Database
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)copy SMILEScopy InChI
Affinity DataKi:  61.6nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M043X2PubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
INSERM U.288

Curated by PDSP Ki Database
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)copy SMILEScopy InChI
Affinity DataKi:  81nMAssay Description:Antagonist activity at human 5HT1A expressed in mouse LM(tK-) cells assessed as inhibition of 5HT-stimulated [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2GG0PubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
INSERM U.288

Curated by PDSP Ki Database
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)copy SMILEScopy InChI
Affinity DataKi:  110nMAssay Description:Inhibition constant against 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2WZ9PubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
INSERM U.288

Curated by PDSP Ki Database
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)copy SMILEScopy InChI
Affinity DataEC50:  27nMAssay Description:Stimulation of [35S]- GIPyS binding to cloned human 5-hydroxytryptamine 1A receptor stably expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W37WVBPubMed