Compile Data Set for Download or QSAR
Found 5 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 1A' and Ligand = 'BDBM50047471'
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Yamanouchi Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50047471((S)-N-tert-butyl-3-(4-(2-methoxyphenyl)piperazin-1...)copy SMILEScopy InChI
Affinity DataKi:  28nMAssay Description:Displacement of [3H]8-OH-DPAT from rat hippocampal 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20R9Q26PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Yamanouchi Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50047471((S)-N-tert-butyl-3-(4-(2-methoxyphenyl)piperazin-1...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:In vitro binding affinity to 5-hydroxytryptamine 1A receptor using [125I](R)-(+)-trans-8-OH-PIPAT as radioligand in rat hippocampal homogenateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24X58F6PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Yamanouchi Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50047471((S)-N-tert-butyl-3-(4-(2-methoxyphenyl)piperazin-1...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:In vitro binding affinity towards the 5-hydroxytryptamine 1A receptor was evaluatedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29W0DJHPubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50047471((S)-N-tert-butyl-3-(4-(2-methoxyphenyl)piperazin-1...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Antagonist activity at human 5-HT1A receptor expressed in CHO-K1 cells co-expressing Galpha16 assessed as decrease in serotonin calcium mobilization ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8H4KPubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Yamanouchi Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50047471((S)-N-tert-butyl-3-(4-(2-methoxyphenyl)piperazin-1...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:In vitro radioligand binding assay on 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT in rat hippocampusMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20R9Q26PubMed