Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 1A' and Ligand = 'BDBM50150105'
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50150105(CHEMBL124069 | [2-(6-Fluoro-chroman-8-yloxy)-ethyl...)copy SMILEScopy InChI
Affinity DataKi:  26.6nMAssay Description:Binding affinity against human 5-hydroxytryptamine 1A receptor in CHO cells labeled with [3H]-8-OH-DPAT radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46RDWPubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50150105(CHEMBL124069 | [2-(6-Fluoro-chroman-8-yloxy)-ethyl...)copy SMILEScopy InChI
Affinity DataKi:  27nMAssay Description:Binding affinity to 5-HT1A receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5WP7PubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50150105(CHEMBL124069 | [2-(6-Fluoro-chroman-8-yloxy)-ethyl...)copy SMILEScopy InChI
Affinity DataKi:  27nMAssay Description:Inhibition constant against 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2WZ9PubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50150105(CHEMBL124069 | [2-(6-Fluoro-chroman-8-yloxy)-ethyl...)copy SMILEScopy InChI
Affinity DataKi:  30nMAssay Description:Agonist activity at 5HT1A receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93BWXPubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50150105(CHEMBL124069 | [2-(6-Fluoro-chroman-8-yloxy)-ethyl...)copy SMILEScopy InChI
Affinity DataIC50: 49nMAssay Description:Inhibition concentration against 5-hydroxytryptamine 1A receptor using cAMP as radioligand in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46RDWPubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50150105(CHEMBL124069 | [2-(6-Fluoro-chroman-8-yloxy)-ethyl...)copy SMILEScopy InChI
Affinity DataIC50: 121nMAssay Description:Inhibition concentrationagainst binding of radioligand [35]GTPgammaS in CHO cells expressing 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46RDWPubMed