Compile Data Set for Download or QSAR
Found 10 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 1A' and Ligand = 'BDBM50151982'
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
China State Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50151982(5-{4-[4-(5-Cyano-1H-indol-3-yl)-butyl]-piperazin-1...)copy SMILEScopy InChI
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5HT1A receptor (unknown origin) expressed in HEK293 cells membranes incubated for 60 mins by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2ZZTPubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
China State Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50151982(5-{4-[4-(5-Cyano-1H-indol-3-yl)-butyl]-piperazin-1...)copy SMILEScopy InChI
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN96NSPubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
China State Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50151982(5-{4-[4-(5-Cyano-1H-indol-3-yl)-butyl]-piperazin-1...)copy SMILEScopy InChI
Affinity DataKi:  9.70nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in CHO-K1 cell membranes incubated for 60 mins by microbeta scintillation counting...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W0996HPubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
China State Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50151982(5-{4-[4-(5-Cyano-1H-indol-3-yl)-butyl]-piperazin-1...)copy SMILEScopy InChI
Affinity DataKi:  28nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZC8701PubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
China State Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50151982(5-{4-[4-(5-Cyano-1H-indol-3-yl)-butyl]-piperazin-1...)copy SMILEScopy InChI
Affinity DataIC50: 0.110nMAssay Description:Inhibition of 5-HT1a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FXDPubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
China State Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50151982(5-{4-[4-(5-Cyano-1H-indol-3-yl)-butyl]-piperazin-1...)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Agonist activity at human 5HT1A expressed in CHO cell membranes assessed as increase in [35S]-GTPgammaS binding after 30 mins by liquid scintillation...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q232008TPubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Merck KGaA

Curated by ChEMBL
LigandPNGBDBM50151982(5-{4-[4-(5-Cyano-1H-indol-3-yl)-butyl]-piperazin-1...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Inhibition of 8-OH DPAT binding to rat hydroxytryptamine 1A receptor expresssed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2513XPSPubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
China State Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50151982(5-{4-[4-(5-Cyano-1H-indol-3-yl)-butyl]-piperazin-1...)copy SMILEScopy InChI
Affinity DataEC50:  0.120nMAssay Description:Agonist activity at human 5-HT1A receptor expressed in HEK293 cells after 60 mins by Eu-cAMP solution based ultra LANCE assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P631ZPubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
China State Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50151982(5-{4-[4-(5-Cyano-1H-indol-3-yl)-butyl]-piperazin-1...)copy SMILEScopy InChI
Affinity DataEC50:  0.790nMAssay Description:Agonist activity at human 5-HT1A receptor expressed in HEK293 cells incubated for 60 mins by Eu-cAMP tracer based LANCE ultra cAMP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4G4CPubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
China State Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50151982(5-{4-[4-(5-Cyano-1H-indol-3-yl)-butyl]-piperazin-1...)copy SMILEScopy InChI
Affinity DataEC50:  0.120nMAssay Description:Agonist activity at human 5H1A receptor expressed in HEK293 cells incubated for 60 mins by Eu-cAMP tracer based LANCE ultra cAMP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87F3NPubMed