Found 13 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 1A' and Ligand = 'BDBM50476734' 
Affinity DataKi: 2.20nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5-HT1A receptor stably expressed in CHO-K1 cell membranes measured after 60 mins by Microbeta2 scintillation...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Pierre Fabre Research Center
Curated by ChEMBL
Pierre Fabre Research Center
Curated by ChEMBL
Affinity DataKi: 2.20nMAssay Description:Binding affinity to 5HT1A receptor in rat cortex membraneMore data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5HT1A receptor stably expressed in CHO-K1 cell membranes measured after 60 mins by microbeta2 sc...More data for this Ligand-Target Pair
Affinity DataEC50: 4.70nMAssay Description:Biased agonist activity at human 5-HT1A receptor stably expressed in CHO-K1 cells assessed as increase in ERK1/2 phosphorylation after 15 mins by Alp...More data for this Ligand-Target Pair
Affinity DataEC50: 60nMAssay Description:Biased agonist activity at human 5-HT1A receptor stably expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation after...More data for this Ligand-Target Pair
Affinity DataEC50: 195nMAssay Description:Biased agonist activity at Gal4-VP16 transcription factor linked human 5-HT1A receptor expressed in human U2OS cells assessed as induction of beta-ar...More data for this Ligand-Target Pair
Affinity DataEC50: 302nMAssay Description:Biased agonist activity at human 5-HT1A receptor stably expressed in CHO-K1 cells co-expressing Galpha16/GPCR assessed as increase in calcium mobiliz...More data for this Ligand-Target Pair
Affinity DataEC50: 195nMAssay Description:Biased agonist activity at Gal4-VP16 transcription factor linked human 5-HT1A receptor expressed in human U2OS cells assessed as stimulation of beta-...More data for this Ligand-Target Pair
Affinity DataEC50: 60nMAssay Description:Biased agonist activity at human recombinant 5-HT1A receptor stably expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumu...More data for this Ligand-Target Pair
Affinity DataEC50: 4.70nMAssay Description:Biased agonist activity at human recombinant 5-HT1A receptor stably expressed in CHO-K1 cells assessed as increase in ERK1/2 phosphorylation levels i...More data for this Ligand-Target Pair
Affinity DataEC50: 389nMAssay Description:Agonist activity at human 5HT1A receptor expressed in C6 cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 245nMAssay Description:Biased agonist activity at human recombinant 5-HT1A receptor stably expressed in CHO-K1 cells assessed as increase in calcium mobilization measured a...More data for this Ligand-Target Pair
