Found 42 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 2B' and Ligand = 'BDBM10755' Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Syntex Discovery Research
Curated by PDSP Ki Database
Syntex Discovery Research
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Syntex Discovery Research
Curated by PDSP Ki Database
Syntex Discovery Research
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Syntex Discovery Research
Curated by PDSP Ki Database
Syntex Discovery Research
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Syntex Discovery Research
Curated by PDSP Ki Database
Syntex Discovery Research
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Syntex Discovery Research
Curated by PDSP Ki Database
Syntex Discovery Research
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Syntex Discovery Research
Curated by PDSP Ki Database
Syntex Discovery Research
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Syntex Discovery Research
Curated by PDSP Ki Database
Syntex Discovery Research
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Syntex Discovery Research
Curated by PDSP Ki Database
Syntex Discovery Research
Curated by PDSP Ki Database
Affinity DataKi: 11nMAssay Description:Displacement of [3H]LSD from human recombinant 5-HT2B receptor expressed in HEK cells by radioligand completion assay relative to controlMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Syntex Discovery Research
Curated by PDSP Ki Database
Syntex Discovery Research
Curated by PDSP Ki Database
Affinity DataKi: 12nMAssay Description:Affinity for human 5-hydroxytryptamine 2B receptor expressed in mammalian cell lineMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Syntex Discovery Research
Curated by PDSP Ki Database
Syntex Discovery Research
Curated by PDSP Ki Database
Affinity DataKi: 12nMAssay Description:Displacement of [3H]5HT from human 5HT2BMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Syntex Discovery Research
Curated by PDSP Ki Database
Syntex Discovery Research
Curated by PDSP Ki Database
Affinity DataKi: 13nMAssay Description:Displacement of [125I]DOI from cloned human 5HT2B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Syntex Discovery Research
Curated by PDSP Ki Database
Syntex Discovery Research
Curated by PDSP Ki Database
Affinity DataKi: 13nMAssay Description:Inhibitory constant against cloned human 5-hydroxytryptamine 2B receptor using with [125I]- DOI radioligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Syntex Discovery Research
Curated by PDSP Ki Database
Syntex Discovery Research
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Syntex Discovery Research
Curated by PDSP Ki Database
Syntex Discovery Research
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2B(Mus musculus (Mouse))
University of Alberta
Curated by PDSP Ki Database
University of Alberta
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Syntex Discovery Research
Curated by PDSP Ki Database
Syntex Discovery Research
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Syntex Discovery Research
Curated by PDSP Ki Database
Syntex Discovery Research
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Syntex Discovery Research
Curated by PDSP Ki Database
Syntex Discovery Research
Curated by PDSP Ki Database
Affinity DataEC50: 0.0708nMAssay Description:Agonist activity at 5-HT2B receptor (unknown origin) by calcium mobilization assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Syntex Discovery Research
Curated by PDSP Ki Database
Syntex Discovery Research
Curated by PDSP Ki Database
Affinity DataEC50: 1.5nMAssay Description:Agonist activity at human 5-HT2B receptor expressed in human Flp-In-293 cells assessed as induction of calcium flux incubated for 1 hr by Fluo-4 dire...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Syntex Discovery Research
Curated by PDSP Ki Database
Syntex Discovery Research
Curated by PDSP Ki Database
Affinity DataEC50: 1.40nMAssay Description:Agonist activity at human 5-HT2B receptor expressed in human Flp-In-293 cells assessed as induction of calcium flux incubated for 1 hr by Fluo-4 dire...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Syntex Discovery Research
Curated by PDSP Ki Database
Syntex Discovery Research
Curated by PDSP Ki Database
Affinity DataEC50: 4.5nMAssay Description:Agonist activity at recombinant human 5-HT2B receptor expressed in CHOK1 cells assessed as increase in inositol1-phosphate accumulation measured afte...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Syntex Discovery Research
Curated by PDSP Ki Database
Syntex Discovery Research
Curated by PDSP Ki Database
Affinity DataEC50: 0.851nMAssay Description:Agonist activity at recombinant human 5HT2B receptor expressed in Flp-In-293 cells assessed as increase in calcium influx measured for 300 secs by Fl...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Syntex Discovery Research
Curated by PDSP Ki Database
Syntex Discovery Research
Curated by PDSP Ki Database
Affinity DataEC50: 0.860nMAssay Description:Agonist activity at recombinant human 5HT2B receptor expressed in Flp-In-293 cells assessed as increase in calcium influx measured for 300 secs by Fl...More data for this Ligand-Target Pair
Affinity DataEC50: 4.20nMAssay Description:Agonist activity at 5HT2b receptor in Wistar rat fundus measured for 90 secsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Syntex Discovery Research
Curated by PDSP Ki Database
Syntex Discovery Research
Curated by PDSP Ki Database
Affinity DataEC50: 25nMAssay Description:Agonist activity at human 5HT2B receptor expressed in HEK293 cells assessed as intracellular IP3 accumulationMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Syntex Discovery Research
Curated by PDSP Ki Database
Syntex Discovery Research
Curated by PDSP Ki Database
Affinity DataEC50: 4.5nMAssay Description:Agonist activity at human 5-HT2BR expressed in CHO cells assessed as induction of IP1 accumulation after 30 mins by HTRF methodMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Syntex Discovery Research
Curated by PDSP Ki Database
Syntex Discovery Research
Curated by PDSP Ki Database
Affinity DataEC50: 1.40nMAssay Description:Agonist activity at human 5-HT2B receptor expressed in Flp-IN HEK293 cells assessed as induction of calcium flux measured every second for 5 mins by ...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Syntex Discovery Research
Curated by PDSP Ki Database
Syntex Discovery Research
Curated by PDSP Ki Database
Affinity DataEC50: 1.5nMAssay Description:Agonist activity at human 5-HT2B receptor expressed in Flp-IN HEK293 cells assessed as induction of calcium flux measured every second for 5 mins by ...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Syntex Discovery Research
Curated by PDSP Ki Database
Syntex Discovery Research
Curated by PDSP Ki Database
Affinity DataEC50: 0.860nMAssay Description:Agonist activity at human 5HT2B receptor expressed in HEK293 cells assessed as calcium flux measured every sec for 3 mins by FLIPR assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Syntex Discovery Research
Curated by PDSP Ki Database
Syntex Discovery Research
Curated by PDSP Ki Database
Affinity DataEC50: 5.80nMAssay Description:Agonist activity at human cloned 5HT2B receptor expressed in HEK293-EBNA cells assessed as myo-[3H]inositol hydrolysisMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Syntex Discovery Research
Curated by PDSP Ki Database
Syntex Discovery Research
Curated by PDSP Ki Database
Affinity DataEC50: 11nMAssay Description:Agonist activity at human recombinant 5HT2B receptor assessed as induction of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Syntex Discovery Research
Curated by PDSP Ki Database
Syntex Discovery Research
Curated by PDSP Ki Database
Affinity DataEC50: 0.5nMAssay Description:Agonist activity at human 5HT2B receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.5nMAssay Description:Activity against 5HT2B receptor in longitudinal stomach fundus strips in wistar ratsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Syntex Discovery Research
Curated by PDSP Ki Database
Syntex Discovery Research
Curated by PDSP Ki Database
Affinity DataEC50: 1.5nMAssay Description:Binding to human 5HT2B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Syntex Discovery Research
Curated by PDSP Ki Database
Syntex Discovery Research
Curated by PDSP Ki Database
Affinity DataEC50: 1.5nMAssay Description:Functional activity against human 5-hydroxytryptamine 2B receptor expressed in CHO cells using fluorometricimaging plate readerMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Syntex Discovery Research
Curated by PDSP Ki Database
Syntex Discovery Research
Curated by PDSP Ki Database
Affinity DataEC50: 0.920nMAssay Description:Agonist activity at human 5-HT2B receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
