Compile Data Set for Download or QSAR
Found 30 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 2C' and Ligand = 'BDBM50001915'
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50001915(1-(3-chlorophenyl)piperazine | CHEMBL478 | m-Chlor...)copy SMILEScopy InChI
Affinity DataKi:  7.90nMAssay Description:Displacement of [125I]DOI from recombinant human 5-HT2C receptor expressed in HEK293 cell membranes after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29025R3PubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50001915(1-(3-chlorophenyl)piperazine | CHEMBL478 | m-Chlor...)copy SMILEScopy InChI
Affinity DataKi:  9nMAssay Description:Displacement of [3H]5HT from human 5HT2CMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3M27PubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50001915(1-(3-chlorophenyl)piperazine | CHEMBL478 | m-Chlor...)copy SMILEScopy InChI
Affinity DataKi:  9nMAssay Description:Affinity for human 5-hydroxytryptamine 2A receptor expressed in mammalian cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B8XG5PubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50001915(1-(3-chlorophenyl)piperazine | CHEMBL478 | m-Chlor...)copy SMILEScopy InChI
Affinity DataKi:  14.1nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M32TBDPubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50001915(1-(3-chlorophenyl)piperazine | CHEMBL478 | m-Chlor...)copy SMILEScopy InChI
Affinity DataKi:  16nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6QTVPubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50001915(1-(3-chlorophenyl)piperazine | CHEMBL478 | m-Chlor...)copy SMILEScopy InChI
Affinity DataKi:  17nMAssay Description:Displacement of [125I]DOI from human recombinant 5HT2C receptor expressed in HEK293E cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K074DKPubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50001915(1-(3-chlorophenyl)piperazine | CHEMBL478 | m-Chlor...)copy SMILEScopy InChI
Affinity DataKi:  17nMAssay Description:Displacement of [125I]DOI from human recombinant 5HT2C expressed in HEK293E cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP74M8PubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50001915(1-(3-chlorophenyl)piperazine | CHEMBL478 | m-Chlor...)copy SMILEScopy InChI
Affinity DataKi:  19.9nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J101QRPubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50001915(1-(3-chlorophenyl)piperazine | CHEMBL478 | m-Chlor...)copy SMILEScopy InChI
Affinity DataKi:  20nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7NDXPubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50001915(1-(3-chlorophenyl)piperazine | CHEMBL478 | m-Chlor...)copy SMILEScopy InChI
Affinity DataKi:  20nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4G8JPubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50001915(1-(3-chlorophenyl)piperazine | CHEMBL478 | m-Chlor...)copy SMILEScopy InChI
Affinity DataKi:  28nMAssay Description:Binding affinity to 5HT2C (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0JC7PubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50001915(1-(3-chlorophenyl)piperazine | CHEMBL478 | m-Chlor...)copy SMILEScopy InChI
Affinity DataKi:  59nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70DD1PubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50001915(1-(3-chlorophenyl)piperazine | CHEMBL478 | m-Chlor...)copy SMILEScopy InChI
Affinity DataKi:  81.3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9GH2PubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50001915(1-(3-chlorophenyl)piperazine | CHEMBL478 | m-Chlor...)copy SMILEScopy InChI
Affinity DataKi:  85.1nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37TWZPubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50001915(1-(3-chlorophenyl)piperazine | CHEMBL478 | m-Chlor...)copy SMILEScopy InChI
Affinity DataKi:  105nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9GSNPubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50001915(1-(3-chlorophenyl)piperazine | CHEMBL478 | m-Chlor...)copy SMILEScopy InChI
Affinity DataKi:  115nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9GSNPubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50001915(1-(3-chlorophenyl)piperazine | CHEMBL478 | m-Chlor...)copy SMILEScopy InChI
Affinity DataKi:  126nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8QP0PubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50001915(1-(3-chlorophenyl)piperazine | CHEMBL478 | m-Chlor...)copy SMILEScopy InChI
Affinity DataKi:  251nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8QP0PubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50001915(1-(3-chlorophenyl)piperazine | CHEMBL478 | m-Chlor...)copy SMILEScopy InChI
Affinity DataKi:  300nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4G8JPubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50001915(1-(3-chlorophenyl)piperazine | CHEMBL478 | m-Chlor...)copy SMILEScopy InChI
Affinity DataKi:  300nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7NDXPubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50001915(1-(3-chlorophenyl)piperazine | CHEMBL478 | m-Chlor...)copy SMILEScopy InChI
Affinity DataKi:  360nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP51R8PubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50001915(1-(3-chlorophenyl)piperazine | CHEMBL478 | m-Chlor...)copy SMILEScopy InChI
Affinity DataEC50:  26nMAssay Description:Binding to human 5HT2C receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3M27PubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50001915(1-(3-chlorophenyl)piperazine | CHEMBL478 | m-Chlor...)copy SMILEScopy InChI
Affinity DataEC50:  15nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in HEK293E cells by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K074DKPubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50001915(1-(3-chlorophenyl)piperazine | CHEMBL478 | m-Chlor...)copy SMILEScopy InChI
Affinity DataEC50:  7.90nMAssay Description:Agonist activity at human 5HT2C receptor expressed in HEK293 cells assessed as intracellular IP3 accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q211BPubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50001915(1-(3-chlorophenyl)piperazine | CHEMBL478 | m-Chlor...)copy SMILEScopy InChI
Affinity DataEC50:  13nMAssay Description:Displacement of [125I]DOI from recombinant human 5-HT2C receptor expressed in HEK293 cell membranes after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29025R3PubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50001915(1-(3-chlorophenyl)piperazine | CHEMBL478 | m-Chlor...)copy SMILEScopy InChI
Affinity DataEC50:  15nMAssay Description:Agonist activity at recombinant human 5-HT2C receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M680ZPubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50001915(1-(3-chlorophenyl)piperazine | CHEMBL478 | m-Chlor...)copy SMILEScopy InChI
Affinity DataEC50:  170nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as induction of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C6XHCPubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50001915(1-(3-chlorophenyl)piperazine | CHEMBL478 | m-Chlor...)copy SMILEScopy InChI
Affinity DataEC50:  15nMAssay Description:Activity at human 5HT2C expressed in HEK293E cells assessed as elevation of intracellular calcium by 384-FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP74M8PubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50001915(1-(3-chlorophenyl)piperazine | CHEMBL478 | m-Chlor...)copy SMILEScopy InChI
Affinity DataEC50:  26nMAssay Description:Functional activity against human 5-hydroxytryptamine 2C receptor expressed in CHO cells using fluorometricimaging plate readerMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B8XG5PubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50001915(1-(3-chlorophenyl)piperazine | CHEMBL478 | m-Chlor...)copy SMILEScopy InChI
Affinity DataEC50:  170nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as induction of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X0674ZPubMed