Compile Data Set for Download or QSAR
Found 8 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 2C' and Ligand = 'BDBM50060417'
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))TBA
LigandPNGBDBM50060417(5-Methyl-3,5-dihydro-2H-pyrrolo[2,3-f]indole-1-car...)copy SMILEScopy InChI
Affinity DataKi:  2.80nMAssay Description:Displacement of [3H]LSD from human recombinant 5-HT2C receptor expressed in HEK cells by radioligand completion assay relative to controlMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9VBRPubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))TBA
LigandPNGBDBM50060417(5-Methyl-3,5-dihydro-2H-pyrrolo[2,3-f]indole-1-car...)copy SMILEScopy InChI
Affinity DataKi:  3.16nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37TWZPubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50060417(5-Methyl-3,5-dihydro-2H-pyrrolo[2,3-f]indole-1-car...)copy SMILEScopy InChI
Affinity DataKi:  5.01nMAssay Description:Displacement of [3H]mesulergine from rat 5-HT2C receptor expressed in HEK293More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75HJFPubMed
Target5-hydroxytryptamine receptor 2C(Mus musculus (Mouse))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50060417(5-Methyl-3,5-dihydro-2H-pyrrolo[2,3-f]indole-1-car...)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:Binding affinity analysed on 5-HT 2C in human clone using [3H]mesulergine as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ09G0PubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))TBA
LigandPNGBDBM50060417(5-Methyl-3,5-dihydro-2H-pyrrolo[2,3-f]indole-1-car...)copy SMILEScopy InChI
Affinity DataKi:  12.0nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W69Q5PubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))TBA
LigandPNGBDBM50060417(5-Methyl-3,5-dihydro-2H-pyrrolo[2,3-f]indole-1-car...)copy SMILEScopy InChI
Affinity DataKi:  13nMAssay Description:Binding affinity towards cloned human 5-hydroxytryptamine 2C receptor expressed in HEK 293 cells using [3H]mesulergine as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1H48PubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))TBA
LigandPNGBDBM50060417(5-Methyl-3,5-dihydro-2H-pyrrolo[2,3-f]indole-1-car...)copy SMILEScopy InChI
Affinity DataKi:  16.2nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M32TBDPubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))TBA
LigandPNGBDBM50060417(5-Methyl-3,5-dihydro-2H-pyrrolo[2,3-f]indole-1-car...)copy SMILEScopy InChI
Affinity DataIC50: 9.40nMAssay Description:Antagonist activity at human recombinant 5-HT2C receptor assessed as inhibition of serotonin-induced inositol phosphate accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N29ZHXPubMed