Found 8 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 2C' and Ligand = 'BDBM50060417'
Affinity DataKi: 2.80nMAssay Description:Displacement of [3H]LSD from human recombinant 5-HT2C receptor expressed in HEK cells by radioligand completion assay relative to controlMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 5.01nMAssay Description:Displacement of [3H]mesulergine from rat 5-HT2C receptor expressed in HEK293More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Mus musculus (Mouse))
Lilly Research Laboratories
Curated by ChEMBL
Lilly Research Laboratories
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Binding affinity analysed on 5-HT 2C in human clone using [3H]mesulergine as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Binding affinity towards cloned human 5-hydroxytryptamine 2C receptor expressed in HEK 293 cells using [3H]mesulergine as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 9.40nMAssay Description:Antagonist activity at human recombinant 5-HT2C receptor assessed as inhibition of serotonin-induced inositol phosphate accumulationMore data for this Ligand-Target Pair