Compile Data Set for Download or QSAR
Found 22 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 2C' and Ligand = 'BDBM50130293'
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))TBA
LigandPNGBDBM50130293(7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...)copy SMILEScopy InChI
Affinity DataKi:  18nMAssay Description:Displacement of [3H]mesulergine from rat cerebral cortex 5HT2C receptor measured after 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8K6MPubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))TBA
LigandPNGBDBM50130293(7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...)copy SMILEScopy InChI
Affinity DataKi:  18nMAssay Description:Binding affinity to 5-HT2C receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R2154CPubMedDrugBank
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))TBA
LigandPNGBDBM50130293(7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...)copy SMILEScopy InChI
Affinity DataKi:  22nMAssay Description:Displacement of [3H]mesulergine from human 5HT2C receptor in human tsA201 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0P1SPubMedDrugBank
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))TBA
LigandPNGBDBM50130293(7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...)copy SMILEScopy InChI
Affinity DataKi:  22nMAssay Description:Binding affinity to 5HT2C receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571DM0PubMedDrugBank
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))TBA
LigandPNGBDBM50130293(7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...)copy SMILEScopy InChI
Affinity DataKi:  22nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639N9TPubMedDrugBank
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))TBA
LigandPNGBDBM50130293(7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...)copy SMILEScopy InChI
Affinity DataKi:  22.4nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2833QKKPubMedDrugBank
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))TBA
LigandPNGBDBM50130293(7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...)copy SMILEScopy InChI
Affinity DataKi:  50nMAssay Description:Displacement of [3H]mesulergine from 5HT2C receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3NW3PubMedDrugBank
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))TBA
LigandPNGBDBM50130293(7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...)copy SMILEScopy InChI
Affinity DataKi:  75nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639N9TPubMedDrugBank
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))TBA
LigandPNGBDBM50130293(7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...)copy SMILEScopy InChI
Affinity DataKi:  76nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639N9TPubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))TBA
LigandPNGBDBM50130293(7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...)copy SMILEScopy InChI
Affinity DataKi:  76nMAssay Description:Displacement of [3H]Mesulergine from rat 5-HT2C receptor expressed in cell membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63PVPPubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))TBA
LigandPNGBDBM50130293(7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...)copy SMILEScopy InChI
Affinity DataKi:  95nMAssay Description:Displacement of [3H]-LSD from 5HT2C receptor (unknown origin) expressed in HEK293T cell membranes measured after 2 hrs by microbeta scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2SS4PubMedDrugBank
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))TBA
LigandPNGBDBM50130293(7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...)copy SMILEScopy InChI
Affinity DataKi:  95nMAssay Description:Displacement of [3H]-LSD from 5HT2C receptor (unknown origin) expressed in HEK293T cell membranes measured after 2 hrs by microbeta scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2SS4PubMedDrugBank
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))TBA
LigandPNGBDBM50130293(7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...)copy SMILEScopy InChI
Affinity DataKi:  97nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639N9TPubMedDrugBank
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))TBA
LigandPNGBDBM50130293(7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...)copy SMILEScopy InChI
Affinity DataKi:  130nMAssay Description:Binding assay using 5-HT2A, Dopamine D2, SERT, αA1, 5-HT2C and H1 Receptors.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28K77RCUS PatentDrugBank
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))TBA
LigandPNGBDBM50130293(7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...)copy SMILEScopy InChI
Affinity DataKi:  180nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639N9TPubMedDrugBank
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))TBA
LigandPNGBDBM50130293(7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...)copy SMILEScopy InChI
Affinity DataKi:  180nMAssay Description:Displacement of [3H]-Mesulergine from human 5-HT2C receptor incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C726CPubMedDrugBank
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))TBA
LigandPNGBDBM50130293(7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...)copy SMILEScopy InChI
Affinity DataKi:  180nMAssay Description:Displacement of [3H]-mesulergine from human 5HT2C receptor by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B34X6PubMedDrugBank
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))TBA
LigandPNGBDBM50130293(7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...)copy SMILEScopy InChI
Affinity DataKi:  250nMpH: 7.4Assay Description:Membranes prepared as above were resuspended to 1 ug protein/ul (measured by Bradford assay using BSA as standard), and 50 ul were added to each well...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41Q6DUS PatentDrugBank
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))TBA
LigandPNGBDBM50130293(7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...)copy SMILEScopy InChI
Affinity DataIC50: 25.7nMAssay Description:(1) The prepared membrane was first applied with appropriate amount of homogenized liquid, and homogenizer was used for evenly dispersing. 15 tubes w...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M06N0US Patent
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))TBA
LigandPNGBDBM50130293(7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...)copy SMILEScopy InChI
Affinity DataIC50: 1.38E+3nMAssay Description:Antagonist activity at 5-HT2C receptor (unknown origin) after 10 mins by calcium 5 dye based FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z03BVSPubMedDrugBank
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))TBA
LigandPNGBDBM50130293(7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...)copy SMILEScopy InChI
Affinity DataIC50: 1.38E+3nMAssay Description:Antagonistic activity at 5-HT2c receptor (unknown origin) after 10 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92DWGPubMedDrugBank
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))TBA
LigandPNGBDBM50130293(7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...)copy SMILEScopy InChI
Affinity DataIC50: 1.38E+3nMAssay Description:Antagonistic activity at 5-HT2c receptor (unknown origin) after 10 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M67N2PubMedDrugBank