Compile Data Set for Download or QSAR
Found 7 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 3A/3B' and Ligand = 'BDBM50000492'
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50000492((zacopride)4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl...)copy SMILEScopy InChI
Affinity DataKi:  0.417nMAssay Description:pKi value for inhibition of [3H]LY-278584 binding to 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM7BQGPubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50000492((zacopride)4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl...)copy SMILEScopy InChI
Affinity DataKi:  0.420nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor in rat cortical membranes using [3H]5-HT as a radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM7BQGPubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50000492((zacopride)4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl...)copy SMILEScopy InChI
Affinity DataKi:  0.420nMAssay Description:In vitro displacement of [3H]-LY 278584 from rat cerebral cortex 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3DGF
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50000492((zacopride)4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl...)copy SMILEScopy InChI
Affinity DataKi:  0.700nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor using [3H]-BRL-43694 in rat posterior cortexMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G160RF
Target5-hydroxytryptamine receptor 3A/3B(Mus musculus (house mouse))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50000492((zacopride)4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl...)copy SMILEScopy InChI
Affinity DataKi:  1.30nMAssay Description:The binding affinity was measured for 5-hydroxytryptamine 3 receptor on NG 108-15 cell line of mouse neuroblastoma-glioma cells in presence of [3H]5 ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VM4FGRPubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50000492((zacopride)4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl...)copy SMILEScopy InChI
Affinity DataKi:  1.5nMAssay Description:Displacement of the 5-hydroxytryptamine 3 receptor ligand [3H]GR-65630 from rat brain cortical membranes.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1M77PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50000492((zacopride)4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Binding affinity was evaluated in vitro by displacement of [3H]zacopride radioligand from 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154HH3