Found 4 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 6' and Ligand = 'BDBM50314760' 
Affinity DataKi: 0.549nM ΔG°: -53.7kJ/mole IC50: 1.18nMpH: 7.4 T: 2°CAssay Description:Determination of tested compounds binding with 5-HT6 receptors was carried out according to the method described in [Monsma F J Jr, Shen Y, Ward R P,...More data for this Ligand-Target Pair
Affinity DataKi: 0.549nMAssay Description:Displacement of [3H]LSD from 5HT6 receptor in humanHeLa cells after 120 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 7.5nMAssay Description:Antagonist activity at human 5HT6 receptor in HEK293 cells assessed as inhibition of serotonin-induced cAMP accumulation pretreated for 15 mins befor...More data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Compounds of general formulas 1 and 2 were tested for their ability to prevent 5-HT6 receptors activation by serotonin. HEK 293 cells (cells of human...More data for this Ligand-Target Pair
