Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = '72 kDa type IV collagenase' and Ligand = 'BDBM12075'
Target72 kDa type IV collagenase(Homo sapiens (Human))
Istituto di Cristallografia

LigandPNGBDBM12075((2S)-2-{[4-(4-bromophenyl)benzene]sulfonamido}-3-m...)copy SMILEScopy InChI
Affinity DataIC50: 4nMpH: 7.0 T: 2°CAssay Description:Inhibition of the matrix metalloproteinases MMP-2, MMP-3, and MMP-8 has been determined by continuously monitoring the hydrolysis of the fluorescent ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348HM7PubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Istituto di Cristallografia

LigandPNGBDBM12075((2S)-2-{[4-(4-bromophenyl)benzene]sulfonamido}-3-m...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:In vitro inhibition of matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T154BFPubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Istituto di Cristallografia

LigandPNGBDBM12075((2S)-2-{[4-(4-bromophenyl)benzene]sulfonamido}-3-m...)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Inhibition of MMP2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC91CRPubMed