Compile Data Set for Download or QSAR
Found 17 Enz. Inhib. hit(s) with Target = '72 kDa type IV collagenase' and Ligand = 'BDBM23971'
Target72 kDa type IV collagenase(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM23971((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)copy SMILEScopy InChI
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of MMP2 after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2P11PubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM23971((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)copy SMILEScopy InChI
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB74DKPubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM23971((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of MMP2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23778J3PubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM23971((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)copy SMILEScopy InChI
Affinity DataIC50: 4.05E+4nMAssay Description:Inhibition of MMP2 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NP25BQPubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM23971((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)copy SMILEScopy InChI
Affinity DataIC50: 4.05E+4nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50NWKPubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM23971((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MMP2 (unknown origin) using succinylated gelatin as substrate preincubated for 10 mins before substrate addition measured after 30 mins...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29888JPPubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM23971((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+5nMAssay Description:Inhibition of human MMP-2 after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1D2TPubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM23971((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)copy SMILEScopy InChI
Affinity DataIC50: 1.56E+5nMAssay Description:Inhibition of recombinant MMP2 using succinylated gelatin as substrate incubated for 10 mins prior to substrate addition measured after 1 hr by UV/VI...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56KS2PubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM23971((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)copy SMILEScopy InChI
Affinity DataIC50: 1.57E+5nMAssay Description:Inhibition of MMP2 after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20R9PKHPubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM23971((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)copy SMILEScopy InChI
Affinity DataIC50: 1.62E+5nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3MMDPubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM23971((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)copy SMILEScopy InChI
Affinity DataIC50: 1.62E+5nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D21XN3PubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM23971((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)copy SMILEScopy InChI
Affinity DataIC50: 1.62E+5nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ10VDPubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM23971((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)copy SMILEScopy InChI
Affinity DataIC50: 1.63E+5nMAssay Description:Inhibition of MMP2 after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2251JKKPubMed
Target72 kDa type IV collagenase(Sus scrofa (Pig))
Shan Dong University

LigandPNGBDBM23971((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)copy SMILEScopy InChI
Affinity DataIC50: 1.63E+5nMAssay Description:Gelatinase A (MMP-2) and TNBS were purchased from Sigma, and the substance was synthesized as described by Vijaykumar et al. The gelatinase, substanc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0D1SPubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM23971((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)copy SMILEScopy InChI
Affinity DataIC50: 1.67E+5nMpH: 8.5 T: 2°CAssay Description:The compound samples were assayed for inhibitory activity against MMP-2 in 96-well microplates using succinylated gelatin as the substrate. The compo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R21083PubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM23971((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)copy SMILEScopy InChI
Affinity DataIC50: 2.53E+5nMAssay Description:Inhibition of MMP2 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67H1ZPubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM23971((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)copy SMILEScopy InChI
Affinity DataIC50: 2.76E+5nMAssay Description:Inhibition of recombinant MMP-2 using succinylated gelatin as substrate incubated for 10 mins before addition of substrate measured after 60 mins by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7JFRPubMed