Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = '72 kDa type IV collagenase' and Ligand = 'BDBM50264811'
Target72 kDa type IV collagenase(Homo sapiens (Human))
University of Athens

Curated by ChEMBL
LigandPNGBDBM50264811(CHEMBL485492 | N-(4-(4-(thiiran-2-ylmethylsulfonyl...)copy SMILEScopy InChI
Affinity DataKi:  110nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD4WM2PubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University of Athens

Curated by ChEMBL
LigandPNGBDBM50264811(CHEMBL485492 | N-(4-(4-(thiiran-2-ylmethylsulfonyl...)copy SMILEScopy InChI
Affinity DataKi:  840nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB281XPubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University of Athens

Curated by ChEMBL
LigandPNGBDBM50264811(CHEMBL485492 | N-(4-(4-(thiiran-2-ylmethylsulfonyl...)copy SMILEScopy InChI
Affinity DataKi:  1.10E+5nMAssay Description:Inhibition of human recombinant MMP2 assessed as hydrolysis of MOCAcPLGLA2pr(Dnp)AR-NH2 by fluorescence spectrofluorometry More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79BSMPubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University of Athens

Curated by ChEMBL
LigandPNGBDBM50264811(CHEMBL485492 | N-(4-(4-(thiiran-2-ylmethylsulfonyl...)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Inhibition of human full length MMP2 using Mca-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 2 hrs prior to testing measured for 15...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29025M9PubMed