Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
Found
1
Enz. Inhib. hit(s) with Target = 'A disintegrin and metalloproteinase with thrombospondin motifs 6' and Ligand = 'BDBM429751'
Target
A disintegrin and metalloproteinase with thrombospondin motifs 6
(Human)
GALAPAGOS NV
US Patent
Ligand
BDBM429751
(5-(3-(4-(4- fluoro-3,5- dimethoxyphenyl) piperidin...)
copy SMILES
copy InChI
Affinity Data
IC50: 12.5nM
Assay Description:
The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
BindingDB Entry DOI:
10.7270/Q2D2211N
US Patent