Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'ATP-dependent translocase ABCB1' and Ligand = 'BDBM50411957'
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50411957(CHEMBL260896)copy SMILEScopy InChI
Affinity DataIC50: 4.17E+3nMAssay Description:Inhibition of human Pgp in A2780 cells after 30 mins by calcein AM assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN67PTPubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50411957(CHEMBL260896)copy SMILEScopy InChI
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of P-glycoprotein-mediated multidrug resistance in adriamycin-resistant human A2780/ADR cells by calcein AM assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63QS6PubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50411957(CHEMBL260896)copy SMILEScopy InChI
Affinity DataIC50: 5.37E+3nMAssay Description:Inhibition of human Pgp in A2780 cells after 30 mins by Hoechst 33342 assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN67PTPubMed