Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'ATP-dependent translocase ABCB1' and Ligand = 'BDBM79181'
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Bulgarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM79181(10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoro...)copy SMILEScopy InChI
Affinity DataKi:  6.50E+3nMAssay Description:Concentration giving half of the maximal ATPase activity calculated for the high-affinity binding site of the CHO P-Glycoprotein (P-gp) in two-affini...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B60VGPubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Bulgarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM79181(10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoro...)copy SMILEScopy InChI
Affinity DataIC50: 6.30E+3nMAssay Description:TP_TRANSPORTER: inhibition of LDS-751 efflux in NIH-3T3-G185 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N82C8PubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Bulgarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM79181(10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoro...)copy SMILEScopy InChI
Affinity DataIC50: 7.20E+3nMAssay Description:TP_TRANSPORTER: inhibition of Daunorubicin efflux in NIH-3T3-G185 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N82C8PubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Bulgarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM79181(10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoro...)copy SMILEScopy InChI
Affinity DataIC50: 1.09E+4nMAssay Description:TP_TRANSPORTER: inhibition of Rhodamine 123 efflux in NIH-3T3-G185 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N82C8PubMed