Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Acetylcholinesterase' and Ligand = 'BDBM10469'
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Mayo Foundation for Medical Education and Research

LigandPNGBDBM10469(Bis-THA inhibitor 1c | Bis-THA inhibitor 8 | CHEMB...)copy SMILEScopy InChI
Affinity DataIC50: 0.770nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4H0PPubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Mayo Foundation for Medical Education and Research

LigandPNGBDBM10469(Bis-THA inhibitor 1c | Bis-THA inhibitor 8 | CHEMB...)copy SMILEScopy InChI
Affinity DataIC50: 0.770nMAssay Description:Inhibition of rat brain Acetylcholinesterase using acetylthiocholine as substrate in presence of BChE inhibitor ethopropazine by spectrophotometric m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87F3NPubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Mayo Foundation for Medical Education and Research

LigandPNGBDBM10469(Bis-THA inhibitor 1c | Bis-THA inhibitor 8 | CHEMB...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of rat brain AChEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154GPXPubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Mayo Foundation for Medical Education and Research

LigandPNGBDBM10469(Bis-THA inhibitor 1c | Bis-THA inhibitor 8 | CHEMB...)copy SMILEScopy InChI
Affinity DataIC50: 31nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43R9QPubMed