Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Acetylcholinesterase' and Ligand = 'BDBM10589'
TargetAcetylcholinesterase(Homo sapiens (Human))
Universitat de Barcelona

LigandPNGBDBM10589(3-Chloro-6,7,10,11-tetrahydro-9-methyl-12-{{8-[(6-...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N7ZB6PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Universitat de Barcelona

LigandPNGBDBM10589(3-Chloro-6,7,10,11-tetrahydro-9-methyl-12-{{8-[(6-...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins prior substrate addition measured after 5 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26974KHPubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM10589(3-Chloro-6,7,10,11-tetrahydro-9-methyl-12-{{8-[(6-...)copy SMILEScopy InChI
Affinity DataIC50: 263nMAssay Description:Inhibition of bovine AChE-induced coumarin-tagged PrP106-126 aggregation after 48 hrs by fluorescence microscopyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26974KHPubMed