Compile Data Set for Download or QSAR
Found 18 Enz. Inhib. hit(s) with Target = 'Acetylcholinesterase' and Ligand = 'BDBM50203126'
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sun Yat-sen University

Curated by ChEMBL
LigandPNGBDBM50203126(3,4-dimethoxy-6,7-dihydro-[1,3]dioxolo[4,5-g]pyrid...)copy SMILEScopy InChI
Affinity DataKi:  289nMAssay Description:Inhibition of electric eel AChE by enzyme kinetics assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50N2TPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50203126(3,4-dimethoxy-6,7-dihydro-[1,3]dioxolo[4,5-g]pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of AChE assessed as hydrolysis of acetylcholine preincubated for 15 mins measured after 15 mins by colorimetric Ellman assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61KN6PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50203126(3,4-dimethoxy-6,7-dihydro-[1,3]dioxolo[4,5-g]pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of AChE (unknown origin) using acetylthiocholine as substrate assessed as substrate hydrolysis by spectrophotometric/Ellman methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59JZPubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sun Yat-sen University

Curated by ChEMBL
LigandPNGBDBM50203126(3,4-dimethoxy-6,7-dihydro-[1,3]dioxolo[4,5-g]pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 374nMAssay Description:Inhibition of electric eel AChE using acetylcholine as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G161V6PubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sun Yat-sen University

Curated by ChEMBL
LigandPNGBDBM50203126(3,4-dimethoxy-6,7-dihydro-[1,3]dioxolo[4,5-g]pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 374nMAssay Description:Inhibition of electric eel AcetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5VP4PubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sun Yat-sen University

Curated by ChEMBL
LigandPNGBDBM50203126(3,4-dimethoxy-6,7-dihydro-[1,3]dioxolo[4,5-g]pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 374nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine chloride substrate as substrate preincubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60PGXPubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sun Yat-sen University

Curated by ChEMBL
LigandPNGBDBM50203126(3,4-dimethoxy-6,7-dihydro-[1,3]dioxolo[4,5-g]pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 374nMAssay Description:Inhibition of electric eel AChE using acetylcholine chloride as substrate preincubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4Q3KPubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sun Yat-sen University

Curated by ChEMBL
LigandPNGBDBM50203126(3,4-dimethoxy-6,7-dihydro-[1,3]dioxolo[4,5-g]pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 374nMAssay Description:Inhibition of electric eel AChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2513ZC5PubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sun Yat-sen University

Curated by ChEMBL
LigandPNGBDBM50203126(3,4-dimethoxy-6,7-dihydro-[1,3]dioxolo[4,5-g]pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 374nMAssay Description:Inhibition of electric eel AChE by modified Ellman methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50N2TPubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sun Yat-sen University

Curated by ChEMBL
LigandPNGBDBM50203126(3,4-dimethoxy-6,7-dihydro-[1,3]dioxolo[4,5-g]pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 374nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine chloride as substrate preincubated for 15 mins prior to substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD70X8PubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sun Yat-sen University

Curated by ChEMBL
LigandPNGBDBM50203126(3,4-dimethoxy-6,7-dihydro-[1,3]dioxolo[4,5-g]pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 374nMAssay Description:Inhibition of electric eel AChE after 15 mins by Ellman's method using acetylcholine as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H1327QPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50203126(3,4-dimethoxy-6,7-dihydro-[1,3]dioxolo[4,5-g]pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 610nMAssay Description:Inhibition of human AChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6TBTPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50203126(3,4-dimethoxy-6,7-dihydro-[1,3]dioxolo[4,5-g]pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate measured for 1 min by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8BXFPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50203126(3,4-dimethoxy-6,7-dihydro-[1,3]dioxolo[4,5-g]pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 770nMpH: 8.0 T: 2°CAssay Description:Briefly, 140 μL of sodium phosphate buffer (pH 8.0), 20 μL of each tested compound with different concentrations (4, 20, and 100 μM) a...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52NH6
TargetAcetylcholinesterase(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50203126(3,4-dimethoxy-6,7-dihydro-[1,3]dioxolo[4,5-g]pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 1.33E+3nMMore data for this Ligand-Target Pair
In DepthDetails
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sun Yat-sen University

Curated by ChEMBL
LigandPNGBDBM50203126(3,4-dimethoxy-6,7-dihydro-[1,3]dioxolo[4,5-g]pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate incubated for 15 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K076RWPubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sun Yat-sen University

Curated by ChEMBL
LigandPNGBDBM50203126(3,4-dimethoxy-6,7-dihydro-[1,3]dioxolo[4,5-g]pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 2.74E+3nMAssay Description:Inhibition of electric eel AChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6TBTPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50203126(3,4-dimethoxy-6,7-dihydro-[1,3]dioxolo[4,5-g]pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 1.74E+4nMAssay Description:Inhibition of recombinant human acetylcholinesterase using acetylthiocholine iodide as substrate preincubated with enzyme for 5 mins followed by subs...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6PQDPubMed