Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with Target = 'Acetylcholinesterase' and Ligand = 'BDBM7458'
TargetAcetylcholinesterase(Homo sapiens (Human))
Institute for Medical Research and Occupational Health

Curated by ChEMBL
LigandPNGBDBM7458(5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one...)copy SMILEScopy InChI
Affinity DataKi:  1.22E+5nMAssay Description:Inhibition of human recombinant AChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP03Q8PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Institute for Medical Research and Occupational Health

Curated by ChEMBL
LigandPNGBDBM7458(5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z97T4
TargetAcetylcholinesterase(Homo sapiens (Human))
Institute for Medical Research and Occupational Health

Curated by ChEMBL
LigandPNGBDBM7458(5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one...)copy SMILEScopy InChI
Affinity DataIC50: 3.42E+3nMMore data for this Ligand-Target Pair
In DepthDetails
TargetAcetylcholinesterase(Rattus norvegicus (rat))TBA
LigandPNGBDBM7458(5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6GXXPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Institute for Medical Research and Occupational Health

Curated by ChEMBL
LigandPNGBDBM7458(5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one...)copy SMILEScopy InChI
Affinity DataIC50: 6.43E+4nMpH: 8.0 T: 2°CAssay Description:Briefly, 140 μL of sodium phosphate buffer (pH 8.0), 20 μL of each tested compound with different concentrations (4, 20, and 100 μM) a...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52NH6
TargetAcetylcholinesterase(Rattus norvegicus (rat))TBA
LigandPNGBDBM7458(5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate measured after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FR0187PubMed