Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Activated CDC42 kinase 1' and Ligand = 'BDBM50421256'
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50421256(CHEMBL2087874)copy SMILEScopy InChI
Affinity DataKi:  0.200nMAssay Description:Inhibition of N-terminal His6-tagged ACK1 expressed in baculovirus infected Hi5 cells assessed as inhibition of autophosphorylation after 2 hrs by EL...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5Q4XPubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50421256(CHEMBL2087874)copy SMILEScopy InChI
Affinity DataKi:  0.300nMAssay Description:Inhibition of ACK1 kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H996XCPubMed
TargetActivated CDC42 kinase 1(Mus musculus)
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50421256(CHEMBL2087874)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of ACK1 in mouse C8 cells assessed as decrease in cell viability after 20 to 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5Q4XPubMed