Compile Data Set for Download or QSAR
Found 27 Enz. Inhib. hit(s) with Target = 'Adenosine receptor A1' and Ligand = 'BDBM21221'
TargetAdenosine receptor A1(Homo sapiens (Human))
University of Virginia

Curated by ChEMBL
LigandPNGBDBM21221((2S,3S,4R,5R)-5-(2-chloro-6-{[(3-iodophenyl)methyl...)copy SMILEScopy InChI
Affinity DataKi:  5.26nMAssay Description:Displacement of [125I]ABA from human adenosine A1 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2833STJPubMed
TargetAdenosine receptor A1(Mus musculus)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM21221((2S,3S,4R,5R)-5-(2-chloro-6-{[(3-iodophenyl)methyl...)copy SMILEScopy InChI
Affinity DataKi:  35nMAssay Description:Displacement of [125I]N6-(4-amino-3-iodobenzyl)adenosine-5'-N-methyl-uronamide from mouse recombinant adenosine A1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8GFHPubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Novo Nordisk A/S

Curated by ChEMBL
LigandPNGBDBM21221((2S,3S,4R,5R)-5-(2-chloro-6-{[(3-iodophenyl)methyl...)copy SMILEScopy InChI
Affinity DataKi:  54nMAssay Description:Binding affinity for adenosine A1 receptor as inhibition of 3[H]-R-PIA binding in rat brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7V3RPubMed
TargetAdenosine receptor A1(Chick)
University of Illinois at Chicago

Curated by PDSP Ki Database
LigandPNGBDBM21221((2S,3S,4R,5R)-5-(2-chloro-6-{[(3-iodophenyl)methyl...)copy SMILEScopy InChI
Affinity DataKi:  74.0nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4TNCPubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University of Virginia

Curated by ChEMBL
LigandPNGBDBM21221((2S,3S,4R,5R)-5-(2-chloro-6-{[(3-iodophenyl)methyl...)copy SMILEScopy InChI
Affinity DataKi:  99nMAssay Description:Binding affinity using [125I]-ABA against human Adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416WDMPubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University of Virginia

Curated by ChEMBL
LigandPNGBDBM21221((2S,3S,4R,5R)-5-(2-chloro-6-{[(3-iodophenyl)methyl...)copy SMILEScopy InChI
Affinity DataKi:  220nMAssay Description:Displacement of [3H]CCPA from human adenosine A1 receptor expressed in CHO cell membranes after 3 hrs by micro beta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41V45PubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University of Virginia

Curated by ChEMBL
LigandPNGBDBM21221((2S,3S,4R,5R)-5-(2-chloro-6-{[(3-iodophenyl)methyl...)copy SMILEScopy InChI
Affinity DataKi:  220nMAssay Description:Displacement of [3H]N6-phenylisopropyladenosine from recombinant human A1AR expressed in CHO cell membranes after 60 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN4709PubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University of Virginia

Curated by ChEMBL
LigandPNGBDBM21221((2S,3S,4R,5R)-5-(2-chloro-6-{[(3-iodophenyl)methyl...)copy SMILEScopy InChI
Affinity DataKi:  220nMAssay Description:Displacement of radioligand from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8GFHPubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University of Virginia

Curated by ChEMBL
LigandPNGBDBM21221((2S,3S,4R,5R)-5-(2-chloro-6-{[(3-iodophenyl)methyl...)copy SMILEScopy InChI
Affinity DataKi:  220nMAssay Description:Displacement of [3H]NECA from human recombinant adenosine A1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69JMJPubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University of Virginia

Curated by ChEMBL
LigandPNGBDBM21221((2S,3S,4R,5R)-5-(2-chloro-6-{[(3-iodophenyl)methyl...)copy SMILEScopy InChI
Affinity DataKi:  220nMAssay Description:Inhibition of [3H]-R-PIA binding to human Adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4P52PubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University of Virginia

Curated by ChEMBL
LigandPNGBDBM21221((2S,3S,4R,5R)-5-(2-chloro-6-{[(3-iodophenyl)methyl...)copy SMILEScopy InChI
Affinity DataKi:  222nMAssay Description:Displacement of [3H]CCPA form human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20R9P71PubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University of Virginia

Curated by ChEMBL
LigandPNGBDBM21221((2S,3S,4R,5R)-5-(2-chloro-6-{[(3-iodophenyl)methyl...)copy SMILEScopy InChI
Affinity DataKi:  222nMAssay Description:Binding affinity towards recombinant human Adenosine A1 receptor was determined using [3H]R-PIA (2.0 nM) as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB24TKPubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University of Virginia

Curated by ChEMBL
LigandPNGBDBM21221((2S,3S,4R,5R)-5-(2-chloro-6-{[(3-iodophenyl)methyl...)copy SMILEScopy InChI
Affinity DataKi:  222nMAssay Description:Displacement of [3H]CCPA from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9QZGPubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University of Virginia

Curated by ChEMBL
LigandPNGBDBM21221((2S,3S,4R,5R)-5-(2-chloro-6-{[(3-iodophenyl)methyl...)copy SMILEScopy InChI
Affinity DataKi:  222nMAssay Description:Displacement of [3H]CCPA from human adenosine A1 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2513XXXPubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University of Virginia

Curated by ChEMBL
LigandPNGBDBM21221((2S,3S,4R,5R)-5-(2-chloro-6-{[(3-iodophenyl)methyl...)copy SMILEScopy InChI
Affinity DataKi:  222nMAssay Description:Displacement of [3H]CCPA from human A1 receptor expressed in CHO cell membranes after 60 mins by gamma counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8HQHPubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University of Virginia

Curated by ChEMBL
LigandPNGBDBM21221((2S,3S,4R,5R)-5-(2-chloro-6-{[(3-iodophenyl)methyl...)copy SMILEScopy InChI
Affinity DataKi:  222nMAssay Description:Displacement of [3H]CCPA from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN38QVPubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University of Virginia

Curated by ChEMBL
LigandPNGBDBM21221((2S,3S,4R,5R)-5-(2-chloro-6-{[(3-iodophenyl)methyl...)copy SMILEScopy InChI
Affinity DataKi:  222nMAssay Description:Displacement of [3H]R-PIA from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4B9ZPubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Novo Nordisk A/S

Curated by ChEMBL
LigandPNGBDBM21221((2S,3S,4R,5R)-5-(2-chloro-6-{[(3-iodophenyl)methyl...)copy SMILEScopy InChI
Affinity DataKi:  820nMAssay Description:Tested for the binding affinity of A1 receptor by displacing the [3H]-PIA in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2348M1VPubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Novo Nordisk A/S

Curated by ChEMBL
LigandPNGBDBM21221((2S,3S,4R,5R)-5-(2-chloro-6-{[(3-iodophenyl)methyl...)copy SMILEScopy InChI
Affinity DataKi:  820nMAssay Description:Displacement of [3H]CCPA from rat adenosine A1 receptor expressed in CHO cells after 60 mins by gamma counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7HDKPubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Novo Nordisk A/S

Curated by ChEMBL
LigandPNGBDBM21221((2S,3S,4R,5R)-5-(2-chloro-6-{[(3-iodophenyl)methyl...)copy SMILEScopy InChI
Affinity DataKi:  820nMAssay Description:Displacement of radioligand from rat adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8GFHPubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Novo Nordisk A/S

Curated by ChEMBL
LigandPNGBDBM21221((2S,3S,4R,5R)-5-(2-chloro-6-{[(3-iodophenyl)methyl...)copy SMILEScopy InChI
Affinity DataKi:  820nMAssay Description:Binding affinity for adenosine A1 receptor as displacement of [3H]R-PIA from rat brain membranes at 10e-4 MMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4QBQPubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University of Virginia

Curated by ChEMBL
LigandPNGBDBM21221((2S,3S,4R,5R)-5-(2-chloro-6-{[(3-iodophenyl)methyl...)copy SMILEScopy InChI
Affinity DataKi:  890nM ΔG°:  -34.5kJ/molepH: 7.4 T: 2°CAssay Description:The membranes prepared from CHO cells transfected with human adenosine A1 receptors were used in binding assays. Nonspecific binding was determined i...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP51JKPubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University of Virginia

Curated by ChEMBL
LigandPNGBDBM21221((2S,3S,4R,5R)-5-(2-chloro-6-{[(3-iodophenyl)methyl...)copy SMILEScopy InChI
Affinity DataKi:  890nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cell membrane after 180 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28918TNPubMed
TargetAdenosine receptor A1(BOVINE)
Universit£ di Camerino

Curated by ChEMBL
LigandPNGBDBM21221((2S,3S,4R,5R)-5-(2-chloro-6-{[(3-iodophenyl)methyl...)copy SMILEScopy InChI
Affinity DataKi:  890nMAssay Description:Displacement of [3H]DPCPX binding to adenosine A1 receptors of bovine cortical membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X29PXPubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University of Virginia

Curated by ChEMBL
LigandPNGBDBM21221((2S,3S,4R,5R)-5-(2-chloro-6-{[(3-iodophenyl)methyl...)copy SMILEScopy InChI
Affinity DataKi:  890nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1MFXPubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University of Virginia

Curated by ChEMBL
LigandPNGBDBM21221((2S,3S,4R,5R)-5-(2-chloro-6-{[(3-iodophenyl)methyl...)copy SMILEScopy InChI
Affinity DataKi:  890nMAssay Description:Displacement of [3H]DPCPX from human A1 adenosine receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5VCSPubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University of Virginia

Curated by ChEMBL
LigandPNGBDBM21221((2S,3S,4R,5R)-5-(2-chloro-6-{[(3-iodophenyl)methyl...)copy SMILEScopy InChI
Affinity DataKi:  1.24E+3nMAssay Description:Displacement of [3H]WIN-35428 from dopamine transporter of rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J105FTPubMed