Compile Data Set for Download or QSAR
Found 9 Enz. Inhib. hit(s) with Target = 'Adenosine receptor A3' and Ligand = 'BDBM50094687'
TargetAdenosine receptor A3(Homo sapiens (Human))TBA
LigandPNGBDBM50094687(1-(8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]t...)copy SMILEScopy InChI
Affinity DataKi:  0.320nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z18GV
TargetAdenosine receptor A3(Homo sapiens (Human))TBA
LigandPNGBDBM50094687(1-(8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]t...)copy SMILEScopy InChI
Affinity DataKi:  0.320nMAssay Description:Displacement of [3H]-MRE3008-F20 from human adenosine A3 receptor expressed in CHO cells; range 0.27-0.34More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D21WWTPubMed
TargetAdenosine receptor A3(Homo sapiens (Human))TBA
LigandPNGBDBM50094687(1-(8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]t...)copy SMILEScopy InChI
Affinity DataKi:  0.320nMAssay Description:Displacement of [3H]-MRE3008-F20 from human Adenosine A3 receptor expressed in HEK cells; range 0.27-0.34More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6BHWPubMed
TargetAdenosine receptor A3(Homo sapiens (Human))TBA
LigandPNGBDBM50094687(1-(8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]t...)copy SMILEScopy InChI
Affinity DataKi:  0.320nMAssay Description:Antagonist activity at human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5P5ZPubMed
TargetAdenosine receptor A3(Homo sapiens (Human))TBA
LigandPNGBDBM50094687(1-(8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]t...)copy SMILEScopy InChI
Affinity DataKi:  0.320nMAssay Description:Displacement of [3H]-MRE3008-F20 from human Adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WQ033HPubMed
TargetAdenosine receptor A3(Homo sapiens (Human))TBA
LigandPNGBDBM50094687(1-(8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]t...)copy SMILEScopy InChI
Affinity DataKi:  0.320nMAssay Description:Binding affinity for human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2183609PubMed
TargetAdenosine receptor A3(Homo sapiens (Human))TBA
LigandPNGBDBM50094687(1-(8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]t...)copy SMILEScopy InChI
Affinity DataKi:  0.320nMAssay Description:Displacement of [3H]NECA from human adenosine A3 receptor expressed in CHO cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N23FXPubMed
TargetAdenosine receptor A3(Homo sapiens (Human))TBA
LigandPNGBDBM50094687(1-(8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]t...)copy SMILEScopy InChI
Affinity DataKi:  324nMAssay Description:Displacement of [3H]MRE3008-F20 from human adenosine A3 receptor expressed in CHO cells after 120 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP766QPubMed
TargetAdenosine receptor A3(Homo sapiens (Human))TBA
LigandPNGBDBM50094687(1-(8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]t...)copy SMILEScopy InChI
Affinity DataIC50: 4.10nMAssay Description:Inhibition of cAMP accumulation in CHO cells expressing human adenosine A3 receptor; range 2.9-6.0More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D21WWTPubMed