Compile Data Set for Download or QSAR
Found 7 Enz. Inhib. hit(s) with Target = 'Adenosine receptor A3' and Ligand = 'BDBM50109451'
TargetAdenosine receptor A3(Homo sapiens (Human))TBA
LigandPNGBDBM50109451(1-(2-(furan-2-yl)-8-methyl-8H-pyrazolo[4,3-e][1,2,...)copy SMILEScopy InChI
Affinity DataKi:  0.430nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z18GV
TargetAdenosine receptor A3(Homo sapiens (Human))TBA
LigandPNGBDBM50109451(1-(2-(furan-2-yl)-8-methyl-8H-pyrazolo[4,3-e][1,2,...)copy SMILEScopy InChI
Affinity DataKi:  0.430nMAssay Description:Binding affinity for human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2183609PubMed
TargetAdenosine receptor A3(Homo sapiens (Human))TBA
LigandPNGBDBM50109451(1-(2-(furan-2-yl)-8-methyl-8H-pyrazolo[4,3-e][1,2,...)copy SMILEScopy InChI
Affinity DataKi:  0.430nMAssay Description:Antagonist activity at human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5P5ZPubMed
TargetAdenosine receptor A3(Homo sapiens (Human))TBA
LigandPNGBDBM50109451(1-(2-(furan-2-yl)-8-methyl-8H-pyrazolo[4,3-e][1,2,...)copy SMILEScopy InChI
Affinity DataKi:  0.430nMAssay Description:Displacement of [3]-MRE-3008F20 from human Adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6BHWPubMed
TargetAdenosine receptor A3(Homo sapiens (Human))TBA
LigandPNGBDBM50109451(1-(2-(furan-2-yl)-8-methyl-8H-pyrazolo[4,3-e][1,2,...)copy SMILEScopy InChI
Affinity DataKi:  0.430nMAssay Description:Displacement of [3H]NECA from human adenosine A3 receptor expressed in CHO cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N23FXPubMed
TargetAdenosine receptor A3(Homo sapiens (Human))TBA
LigandPNGBDBM50109451(1-(2-(furan-2-yl)-8-methyl-8H-pyrazolo[4,3-e][1,2,...)copy SMILEScopy InChI
Affinity DataKi:  427nMAssay Description:Displacement of [3H]MRE3008-F20 from human adenosine A3 receptor expressed in CHO cells after 120 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP766QPubMed
TargetAdenosine receptor A3(Homo sapiens (Human))TBA
LigandPNGBDBM50109451(1-(2-(furan-2-yl)-8-methyl-8H-pyrazolo[4,3-e][1,2,...)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMAssay Description:Inhibition of IB-MECA agonist-mediated cAMP production in membranes of CHO cells expressing human Adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6BHWPubMed