Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Aldo-keto reductase family 1 member C2' and Ligand = 'BDBM50533577'
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))TBA
LigandPNGBDBM50533577(CHEMBL1236131 | US11459295, Compound (S) 4b)copy SMILEScopy InChI
Affinity DataIC50: 1.35E+3nMAssay Description:the inhibitory potency of the individual compounds against the AKR1C isoforms was determined by monitoring the NADP+ dependent oxidation of S-tetralo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0Z58US Patent
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))TBA
LigandPNGBDBM50533577(CHEMBL1236131 | US11459295, Compound (S) 4b)copy SMILEScopy InChI
Affinity DataIC50: 1.35E+3nMAssay Description:Inhibition of human recombinant AKR1C2 using S-tetralol as substrate assessed as reduction in NADP+-dependent S-tetralol oxidation preincubated for 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z47WNPubMed