Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Aldo-keto reductase family 1 member C3' and Ligand = 'BDBM50533575'
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))TBA
LigandPNGBDBM50533575(CHEMBL4447175 | US11459295, Compound LM5885 (+-) 7)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:the inhibitory potency of the individual compounds against the AKR1C isoforms was determined by monitoring the NADP+ dependent oxidation of S-tetralo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0Z58US Patent
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))TBA
LigandPNGBDBM50533575(CHEMBL4447175 | US11459295, Compound LM5885 (+-) 7)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human recombinant AKR1C3 using S-tetralol as substrate assessed as reduction in NADP+-dependent S-tetralol oxidation preincubated for 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z47WNPubMed