Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with Target = 'Alpha-1A adrenergic receptor' and Ligand = 'BDBM50048803'
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50048803(5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)et...)copy SMILEScopy InChI
Affinity DataKi:  0.5nMAssay Description:Displacement of [3H]prazosin from rat adrenergic alpha1A receptor expressed in fibroblast cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2611023PubMed
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50048803(5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)et...)copy SMILEScopy InChI
Affinity DataKi:  1.90nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2TQBPubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Mayo Foundation for Medical Education and Research and Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50048803(5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)et...)copy SMILEScopy InChI
Affinity DataKi:  2.60nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057DHPPubMedDrugBank
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Mayo Foundation for Medical Education and Research and Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50048803(5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)et...)copy SMILEScopy InChI
Affinity DataKi:  6nMAssay Description:Binding assay using 5-HT2A, Dopamine D2, SERT, αA1, 5-HT2C and H1 Receptors.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28K77RCUS PatentDrugBank
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50048803(5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)et...)copy SMILEScopy InChI
Affinity DataKi:  12nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2610XV6PubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Mayo Foundation for Medical Education and Research and Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50048803(5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)et...)copy SMILEScopy InChI
Affinity DataKi:  18nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2833QKKPubMedDrugBank