Compile Data Set for Download or QSAR
Found 11 Enz. Inhib. hit(s) with Target = 'Alpha-2B adrenergic receptor' and Ligand = 'BDBM50016897'
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50016897(2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2) ...)copy SMILEScopy InChI
Affinity DataKi:  6.20nMAssay Description:Binding affinity towards human Alpha-2B adrenergic receptor by the displacement of [3H]rauwolscineMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ70ZD
TargetAlpha-2B adrenergic receptor(NEONATAL RAT)
Allergan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50016897(2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2) ...)copy SMILEScopy InChI
Affinity DataKi:  8.30nMAssay Description:Compound was tested in vitro for binding affinity against Alpha-2B adrenergic receptor from cloned rat RNG receptor transfected into Chinese hamster ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC31GFPubMed
TargetAlpha-2B adrenergic receptor(NEONATAL RAT)
Allergan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50016897(2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2) ...)copy SMILEScopy InChI
Affinity DataKi:  8.30nMAssay Description:Binding affinity for rat Alpha-2B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ889JPubMed
TargetAlpha-2B adrenergic receptor(OPOSSUM)
University of Missouri

Curated by PDSP Ki Database
LigandPNGBDBM50016897(2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2) ...)copy SMILEScopy InChI
Affinity DataKi:  14nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25H7DS8PubMed
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50016897(2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2) ...)copy SMILEScopy InChI
Affinity DataKi:  32nMAssay Description:Displacement of [3H]RX821001 from human alpha2B adrenoceptor expressed in CHO cells after 60 mins by gamma counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1Z9QPubMed
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50016897(2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2) ...)copy SMILEScopy InChI
Affinity DataKi:  39.8nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28P5Z2CPubMed
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50016897(2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2) ...)copy SMILEScopy InChI
Affinity DataKi:  69.2nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72G01PubMed
TargetAlpha-2B adrenergic receptor(NEONATAL RAT)
Allergan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50016897(2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2) ...)copy SMILEScopy InChI
Affinity DataKi:  160nMAssay Description:in vitro alpha-2B adrenergic receptor binding assay from rats ,using RX 821002 as the displaceable ligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C828HKPubMed
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50016897(2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2) ...)copy SMILEScopy InChI
Affinity DataKi:  309nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28P5Z2CPubMed
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50016897(2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2) ...)copy SMILEScopy InChI
Affinity DataEC50:  166nMAssay Description:Agonistic activity towards human Alpha-2B adrenergic receptor was measured as ability to inhibit forskolin-stimulated synthesis of cyclic adenosine m...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ70ZD
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50016897(2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2) ...)copy SMILEScopy InChI
Affinity DataEC50:  1.18E+3nMAssay Description:Agonist activity at human alpha2B adrenoceptor expressed in CHO cells assessed as induction of extracellular acidification by microphysiometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B32JFPubMed